What are CYP isoenzymes?

Prepare for Lehne's Pharmacotherapeutics Test with comprehensive study guides, flashcards, and detailed multiple-choice questions. Each question is crafted with insights and explanations to help you understand and ace your exam effortlessly!

CYP isoenzymes, or cytochrome P450 enzymes, play a crucial role in drug metabolism, primarily occurring in the liver. These enzymes facilitate the chemical reactions that transform lipophilic chemical compounds, such as drugs, into more hydrophilic metabolites that can be easily excreted from the body. This metabolic process is essential for the detoxification and elimination of drugs and other xenobiotics.

By breaking down drugs, CYP isoenzymes can affect the efficacy and toxicity of medications, influencing how they are used in therapy. Their activity can vary significantly between individuals due to genetic differences, interactions with other substances, and environmental factors, which is why understanding their functions is important for personalized medicine. This metabolic capability distinctly aligns with the role indicated in the selected answer.

The other options do not accurately describe CYP isoenzymes, as they do not involve protein breakdown in the stomach, allergic reactions, or medication absorption enhancement.

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